Cytomegalovirus infection usually goes unnoticed in healthy people, but it can be fatal in immunocompromised people such as HIV-infected people, organ transplant recipients, or newborn babies.
 
Seronegative female patients infected during pregnancy can transmit the disease to the developing fetus, resulting in congenital abnormalities.
 
The Cytomegalovirus-IgG test is important for assessing the patient immunity status and detecting seroconversion.
 
A significant increase in the anti-cytomegalovirus IgG titer is indicative of a recent or past infection or reactivation of a latent infection.